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EIA Kits

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CanAg S100BB EIA (RUO)

This product is available for Research Use Only and is not for use in diagnostic procedures.

S100 is a 20 kDa protein belonging to the S100/calmodulin/troponin C super family of EF-hand calcium-binding proteins. S100 was originally isolated from human brain and is considered a glial-cell specific protein1. Today, 20 monomers of the S100 family have been identified based on structural and functional similarities2, 3. Most of the S100 proteins exist as dimers and are expressed in a cell-specific manner. Two of the S100 monomers, designated S100A1 and S100B4 are highly conserved between species and are found as homodimers (BB) and heterodimers (A1B) in central nervous system glial cells and in certain peripheral cells (ie, Schwann cells, melanocytes, adipocytes, and chondrocytes)5.

The CanAg S100BB EIA is a solid-phase, noncompetitive assay based on the direct sandwich technique for optimal clinical sensitivity, specificity, and nonspecific interference for determination of the S100BB isoform. The assay is based on an antibody specific for the S100BB dimer as capture and HRP-labeled MAb specific for S100B for detection.

Download our CanAg S100BB product information:

CANAG S100BB EIA (RUO) - FULL PACKAGE INSERT
CANAG S100BB EIA - MATERIAL SAFETY DATA SHEET

Covered by US Patent 6,555,327

Product no: 701-85